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Flow-Enhanced Vascularization and Maturation of Kidney Organoids In Vitro
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Kim Homan, Navin Gupta and co-workers have demonstrated an in vitro method for culturing kidney organoids under flow on millifluidic chips, which expands their endogenous pool of endothelial progenitor cells, promotes the formation of perfusable vascular networks, and enhances the maturation of tubular and glomerular compartments.